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The 18 Best Antiperspirants for Excessive Sweating in 2022

March 11, 2022 6 min read

best antiperspirant for excessive sweating

Living with hyperhidrosis, or excessive sweating, can be exhausting and expensive. Keeping dry and smelling fresh is vital to feeling confident so it may be disappointing when your personal hygiene product lets you down.

You work so hard to prevent (and hide) sweat marks on your clothing... so finding an antiperspirant product for heavy sweating that doesn’t break the bank is a must! The good news is that you don’t need to visit a doctor to get powerful antiperspirants for excessive sweating.

If you suffer from excessive sweating, then you may be all too familiar with embarrassing sweat marks and unwelcome body odor. But never fear: we’ve compiled a list of the 18 best antiperspirants and antiperspirant deodorants for excessive sweating. Keep reading to learn about these top-ranking products.

  1. SweatBlock Clinical Strength Antiperspirant Wipes
  2. Carpe Underarm Antiperspirant and Deodorant
  3. Duradry 3-Step Protection System
  4. ZeroSweat Antiperspirant Deodorant
  5. Jack Black Pit Boss Antiperspirant Deodorant
  6. Duradry AM Deodorant and Antiperspirant
  7. Duradry PM Antiperspirant Gel
  8. Arm & Hammer UltraMax Antiperspirant Deodorant
  9. Gillette Clinical Strength Antiperspirant Deodorant
  10. Right Guard Xtreme Defense Antiperspirant Deodorant
  11. Certain Dri Prescription Strength Antiperspirant
  12. Degree Men Antiperspirant Deodorant Dry Spray
  13. Maxim Prescription Strength Antiperspirant & Deodorant
  14. Certain Dri Extra Strength Antiperspirant Deodorant
  15. SweatBlock Antiperspirant Roll-on
  16. Perspirex Original Antiperspirant Roll-on
  17. ZeroSweat Antiperspirant Deodorant with Aloe
  18. Old Spice High Endurance Antiperspirant Deodorant

This post was originally published in February 2020, and was updated in February 2021, January 2022 and March 2022.

What's the Difference Between Antiperspirant & Antiperspirant Deodorant?

It’s common to use the terms antiperspirant and deodorant interchangeably. But they actually serve two completely different purposes. Antiperspirant is designed to stop sweat. Deodorant is designed to mask or neutralize body odor.

An antiperspirant deodorant is just what its name suggests: a combination of antiperspirant and deodorant. It has the active ingredients of an antiperspirant to block sweat glands and the odor-fighting properties of a deodorant. 

In this post, we include both antiperspirants (to stop sweat) and antiperspirant deodorants (to stop sweat and neutralize body odor). Now let's get to the list!

1. SweatBlock Clinical Strength Antiperspirant Wipes

As an alternative to traditional antiperspirant, try SweatBlock Clinical Strength Antiperspirant Wipes. They offer freedom from excessive sweat and embarrassing sweat marks.

The wipes contain a trade-secret formula for wetness prevention that can be effective for up to 7 days. Comes with a money-back guarantee. Buy on Amazon.

2. Carpe Underarm Antiperspirant and Deodorant

Treat excessive perspiration this dermatologist-recommended clinical grade antiperspirant from Carpe. The patent-pending formula reduces sweat to help control hyperhidrosis symptoms without a prescription.

The antiperspirant lotion is non-greasy and non-irritating and soothes and moisturizes skin. Apply a pea-sized amount daily to clean, dry underarms. Buy on Amazon.

An antiperspirant deodorant has the active ingredients of an antiperspirant and the odor-fighting properties of a deodorant.

3. Duradry 3-Step Protection System

The Duradry System offers freedom from excessive sweating in three steps. First, bathe with the Duradry Wash to prepare your skin for the antiperspirant.

After bathing and before you go to sleep, apply the Duradry PM to control sweating while you sleep. In the morning, use Duradry AM to keep your armpits dry and odor-free throughout the day. When used properly and together, you can achieve positive results within a few days. Buy on Amazon.

4. ZeroSweat Antiperspirant Deodorant

ZeroSweat gives clinical strength protection by stopping underarm sweat production. While other antiperspirants work by blocking sweat glands, ZeroSweat simply stops the sweat glands from working at all.

As a contender for the best antiperspirant for excessive sweating, it can provide sweat and odor protection for up to 7 days. Buy on Amazon.

5. Jack Black Pit Boss Antiperspirant Deodorant

Among the strongest antiperspirant for males, Jack Black Pit Boss provides powerful protection against odor and sweat. It comes in a clear solid stick that doesn’t leave residue on your shirts or skin. The dermatologist-tested formula is designed for sensitive skin and prevents skin irritation. Buy on Amazon.

6. Duradry AM Deodorant and Antiperspirant

Feel confident all day with AM Deodorant and Antiperspirant from Duradry. This morning formula works to stop excessive sweating and odors. Dermatologists have tested and recommended this antiperspirant to combat hyperhidrosis.

Every morning, apply it to your underarms without fear of it leaving marks on clothes. Buy on Amazon.

7. Duradry PM Antiperspirant Gel

Stay confident wherever you go with this antiperspirant for heavy sweating from Duradry. Formulated with aluminum chloride hexahydrate and salicylic acid, the unscented gel antiperspirant helps control sweat.

Experience prescription strength protection from a pea-sized amount applied at bedtime. Each tube provides 8 weeks of protection. For best results, use with Duradry AM stick deodorant. Buy on Amazon.

You don’t need to visit your doctor to get clinical-strength antiperspirants for excessive sweating.

8. Arm & Hammer UltraMax Antiperspirant Deodorant

Arm & Hammer’s UltraMax is a long-lasting antiperspirant for heavy sweating that also acts as a deodorant. It shuts down perspiration and odors all day long with its Advanced Sweat Control Technology. This affordable option is available as solid or gel. Buy on Amazon.

9. Gillette Clinical Strength Antiperspirant Deodorant

Gillette Clinical Strength Antiperspirant Deodorant is an effective men's antiperspirant for excessive sweating. It provides the same wetness protection as a prescription-strength product containing 6.25% Aluminum Chloride.

It provides 48 hours of sweat protection and contains 10,000 odor-fighting molecules. It comes in a gel to provide clear application. Buy on Amazon.

10. Right Guard Xtreme Defense Antiperspirant Deodorant

Right Guard Xtreme Defense takes freshness to “Xtreme” levels. It provides reliable protection from excessive sweat and body odor for up to 72 hours after a single application. It is made from ingredients tested by dermatologists to prevent skin irritation. Available in solid or a gel application. Buy on Amazon.

11. Certain Dri Prescription Strength Antiperspirant

You don’t need a prescription to pick up Certain Dri Prescription Strength Clinical Antiperspirant. It ranks as one of the best over the counter antiperspirants you can find without a doctor’s visit.

This roll-on contains 12% Aluminum Chloride, the active ingredient recommended by doctors to treat hyperhidrosis. It offers up to 72 hours of protection. Buy on Amazon.

12. Degree Men Antiperspirant Deodorant Dry Spray

This product by Degree is also designed for men who are active and on the go. The spray application ensures fast-drying and clean-feeling protection instantaneously.

Its Motionsense technology detects movement, then activates the antiperspirant. The unique technology, paired with 48-hour protection, makes this dry spray a winning deodorant and antiperspirant combination. Buy on Amazon.

13. Maxim Prescription Strength Antiperspirant & Deodorant

Maxim Prescription Strength Antiperspirant & Deodorant is a clinical strength product recommended by doctors for excessive sweating. This roll-on provides notable protection from sweat and odor for up to a week if properly applied. It is made without alcohol. Buy on Amazon.

14. Certain Dri Extra Strength Antiperspirant Deodorant

Certain Dri is known for its effective and long-lasting clinical strength antiperspirant formulas. This product provides odor protection along with an extra-strength, sweat stopping formula that lasts up to 72 hours.

Not only is it one of the best men's antiperspirant deodorants for sweating, it is also gentle on sensitive skin. Buy on Amazon.

15. SweatBlock Antiperspirant Roll-on

Sweat Block is one of the most powerful antiperspirants for hyperhidrosis and excessive sweating. The prescription-strength antiperspirant roll-on contains Aluminum Chloride to protect against sweat. Its unscented formula is safe, effective, and time-tested.

Apply at night before going to bed, wash off in the morning, and you'll be sweat-free for up to 7 days. Buy on Amazon.

16. Perspirex Original Antiperspirant Roll-on

Perspirex Original Antiperspirant has been proven to combat sweat and odor for at least 3 days without losing efficacy. The APX skin care system protects against irritation and the patented formula provides ultimate sweat protection.

Apply at night to clean, dry skin and allow it to dry completely. In the morning, wash your armpits with soap and water. Buy on Amazon.

There is no additional benefit to applying more antiperspirant than recommended.

17. ZeroSweat Antiperspirant Deodorant with Aloe

This gentler alternative to the original ZeroSweat is designed to be gentle on your skin. Soothing chamomile and aloe protect your skin. Once the clinical strength formula is absorbed, it stops sweat production for up to 7 days.

It is made from safe, pure, and quality ingredients making it one of the most powerful antiperspirants for sensitive skin. Buy on Amazon.

18. Old Spice High Endurance Antiperspirant Deodorant

The High Endurance collection from Old Spice features its classic scent and provides 48-hour protection against sweat and odor. It comes in a stick form that goes on clear so you don’t have to worry about residue on your clothes or skin.

This highly effective product keeps you feeling fresh, and may even be the best smelling antiperspirant deodorant on the list. Buy on Amazon.

More ways to stop sweat stains

If your current antiperspirant has left you wanting or soaked, try one of these highly effective antiperspirants for excessive sweating. Be sure to follow our application guidelines to get the best results.

To ensure you get all-day protection, try an Ejis sweat proof undershirt (buy in our shop or on Amazon). Our sweat proof undershirts are designed to protect your shirts from sweat marks and stains. They are also infused with real silver to help fight odor-causing bacteria.

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Ejis, Inc. is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Some links on this page provide us a commission at no additional cost to you.

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