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Living with hyperhidrosis, or excessive sweating, can be exhausting and expensive. Keeping dry and smelling fresh is vital to feeling confident, so it may be disappointing when your personal hygiene product lets you down. You work so hard to prevent (and hide) sweat marks on your clothing, so finding the best antiperspirant for excessive sweating that doesn’t break the bank is a must!
The good news is that you don’t need to visit a doctor to get powerful antiperspirants for excessive sweating. There are many over-the-counter clinical strength products designed to stop keep sweat at bay. And we’ve compiled a list of the 17 best antiperspirants for excessive sweating to help you in your pursuit.
This post was originally published in February 2020 and was updated in 2021, 2022, 2023, 2024, 2025.
It’s common to use the terms antiperspirant and deodorant interchangeably. But they serve two completely different purposes. Antiperspirant is designed to stop sweat. Deodorant is designed to mask or neutralize body odor.
An antiperspirant deodorant is just what its name suggests: a combination of antiperspirant and deodorant. It has the active ingredients of an antiperspirant to block sweat glands and the odor-fighting properties of a deodorant.
In this post, we include both antiperspirants (to stop sweat) and antiperspirant deodorants (to stop sweat and neutralize body odor). Now, let's get to the list!
Discover the Carpe Clinical Grade Underarm Regimen, your solution to excessive sweating. This dermatologist-recommended, three-step process is simple: cleanse with the Exfoliator, use an Antiperspirant Wipe at night, and apply the Antiperspirant Stick each morning. Bid farewell to sweat pads and enjoy dry, fresh underarms for restored confidence and comfort. (Buy on Amazon)
As an alternative to traditional antiperspirants, try SweatBlock Clinical Strength Antiperspirant Wipes. They offer freedom from excessive sweat and embarrassing sweat marks. The wipes contain a trade-secret formula for wetness prevention that can be effective for up to 7 days. This product comes with a money-back guarantee. (Buy on Amazon)
Maxim Prescription Strength Antiperspirant Deodorant is a clinical strength product recommended by doctors for excessive sweating. This unscented roll-on provides notable protection from sweat and odor for up to a week if properly applied. It is made without alcohol so it won't dry out your skin. For best results, apply to clean skin at night. (Buy on Amazon)
You don’t need to visit a doctor to get powerful antiperspirants for excessive sweating
Stay confident wherever you go with this antiperspirant for heavy sweating from Duradry. Formulated with aluminum chloride hexahydrate and salicylic acid, the unscented gel antiperspirant helps control sweat. Experience prescription-strength protection from a pea-sized amount applied at bedtime. Each tube provides 8 weeks of protection. (Buy on Amazon)
Treat excessive perspiration with this dermatologist-recommended clinical-grade antiperspirant from Carpe. The patent-pending formula reduces sweat to help control hyperhidrosis symptoms without a prescription. This antiperspirant lotion is non-greasy and non-irritating and soothes and moisturizes the skin. Apply a pea-sized amount daily to clean, dry underarms. (Buy on Amazon)
The Duradry System offers freedom from excessive sweating in three steps. First, bathe with Duradry Wash to prepare your skin for the antiperspirant. After bathing and before you go to sleep, apply Duradry PM to control sweating while you sleep. In the morning, use Duradry AM to keep your armpits dry and odor-free throughout the day. When used properly and together, you can achieve positive results within a few days. (Buy on Amazon)
Feel confident all day with AM Deodorant and Antiperspirant from Duradry. This morning formula works to stop excessive sweating and odors. Dermatologists have tested and recommended this antiperspirant to combat hyperhidrosis. Every morning, apply it to your underarms without fear of it leaving marks on your clothes. (Buy on Amazon)
The High Endurance collection from Old Spice features its classic scent and provides 48-hour protection against sweat and odor. It comes in a stick form that goes on clear, so you don’t have to worry about residue on your clothes or skin. This highly effective product keeps you feeling fresh and may even be the best-smelling antiperspirant deodorant on the list. (Buy on Amazon)
Gillette Clinical Strength Antiperspirant Deodorant is an effective men's antiperspirant for excessive sweating. It provides the same wetness protection as a prescription-strength product containing 6.25% Aluminum Chloride. It provides 48 hours of sweat protection and contains 10,000 odor-fighting molecules. It comes in a gel to provide a clear application. (Buy on Amazon)
You don’t need a prescription to pick up Certain Dri Prescription Strength Clinical Antiperspirant. It ranks as one of the best over-the-counter antiperspirants you can find without a doctor’s visit. This roll-on contains 12% Aluminum Chloride, the active ingredient recommended by doctors to treat hyperhidrosis. It offers up to 72 hours of protection. (Buy on Amazon)
Sweat Block is one of the most powerful antiperspirants for hyperhidrosis and excessive sweating. The prescription-strength antiperspirant roll-on contains Aluminum Chloride to protect against sweat. Its unscented formula is safe, effective, and time-tested. Apply at night before going to bed, wash off in the morning, and you'll be sweat-free for up to 7 days. (Buy on Amazon)
Among the strongest antiperspirant for males, Jack Black Pit Boss provides powerful protection against odor and sweat. It comes in a clear solid stick that doesn’t leave residue on your shirts or skin. The dermatologist-tested formula is designed for sensitive skin and prevents skin irritation. (Buy on Amazon)
ZeroSweat gives clinical-strength protection by stopping underarm sweat production. While other antiperspirants work by blocking sweat glands, ZeroSweat simply stops the sweat glands from working at all. As a contender for the best antiperspirant for excessive sweating, it can provide sweat and odor protection for up to 7 days. (Buy on Amazon)
Arm & Hammer’s UltraMax is a long-lasting antiperspirant for heavy sweating that also acts as a deodorant. It shuts down perspiration and odors all day long with its Advanced Sweat Control Technology. This affordable option is available as solid or gel. (Buy on Amazon)
Certain Dri is known for its effective and long-lasting clinical strength antiperspirant formulas. This product provides odor protection along with an extra-strength, sweat-stopping formula that lasts up to 72 hours. Not only is it one of the best men's antiperspirant deodorants for sweating, it is also gentle on sensitive skin. (Buy on Amazon)
This product by Degree is also designed for men who are active and on the go. Its Motionsense technology detects movement, then activates the antiperspirant. The unique technology, paired with 72-hour protection against sweat and odor, makes this product a winning deodorant and antiperspirant combination. (Buy on Amazon)
Perspirex Original Antiperspirant has been proven to combat sweat and odor for at least 3 days without losing efficacy. The APX skin care system protects against irritation and the patented formula provides ultimate sweat protection. Apply at night to clean, dry skin and allow it to dry completely. In the morning, wash your armpits with soap and water. (Buy on Amazon)
If your current antiperspirant has left you wanting or soaked, try one of these highly effective antiperspirants for excessive sweating. Be sure to follow the product's application guidelines to get the best results.
We have also compiled a list of home remedies to help with symptoms from hyperhidrosis.
To ensure you get all-day protection, try an Ejis sweat proof undershirt (buy in our shop or on Amazon). Our sweat proof undershirts are designed to protect your shirts from sweat marks and stains. They are also infused with real silver to help fight odor-causing bacteria.
Ejis, Inc. is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com. Some links on this page provide us a commission at no additional cost to you.
Sweating is the body’s natural response to an increase in temperature; it helps cool us down. You’ve heard about sweaty armpits and sweat patches on the back of shirts, but a less-discussed sweat zone is the head and face. Sweating in this area can leave you feeling even more exposed, as we often present and express ourselves with our faces. Keep reading for our list of the best antiperspirants for facial sweating.
